Potassium iodide

Consult latest REMM online version for current details.

http://www.remm.nlm.gov/int_contamination.htm#blockingagents

Administered for Isotopes
--FDA approved for Iodine-131

Route of Administration
--PO
--Pills are available for adults.
--Liquid is available for young children and those unable to take pills.

Dosage
Adults >40 years
--130 mg/day (For projected thyroid dose ≥500 cGy)
Adults 18 - 40 years
--130 mg/day (For projected thyroid dose ≥10 cGy)
Pregnant or lactating women of any age
--130 mg/day (For projected thyroid dose ≥5 cGy)
Adolescents ≥70 kg
--130 mg/day (For projected thyroid dose ≥5 cGy)
Children & adolescents 3 - 18 years
--65 mg/day (For projected thyroid dose ≥5 cGy)
Infants & toddlers 1 month - 3 years
--32.5 mg/day (For projected thyroid dose ≥5 cGy)
Neonates from birth - 1 year
--16 mg/day (For projected thyroid dose ≥5 cGy)

Duration of treatment
--Some incidents will require only a single dose of KI.
--Incident managers may recommend additional daily doses if ongoing radioactive iodine ingestion or inhalation represents a continuing threat.
--See details on REMM

Mechanism of action
--Blocking agent